Research and Impact Report 2024

The 2024 Research and Impact Report highlights the significant achievements and milestones of the National Centre for Young People with Epilepsy Charitable Trust. This year has been marked by substantial progress in paediatric epilepsy research, with numerous active projects, new studies, and impactful publications.

Led by Professor Helen Cross, the research programme is a collaborative effort between Young Epilepsy, Great Ormond Street Hospital, and UCL GOS - Institute of Child Health. This partnership leverages multidisciplinary expertise to improve diagnosis, treatment, and support for children with epilepsy.

Key Achievements

  • Active Projects: In 2024, the programme conducted 46 active projects, launched 8 new studies, and completed 3. Notable projects include investigations into DNA methylation in epilepsy, development of zebrafish models for genetic disorders, and a study on physical activity in children with epilepsy.
  • Publications: Between July 2023 and June 2024, the team produced 86 peer-reviewed research articles, 27 reviews, and a book chapter. Five publications ranked among the top 5% globally.
  • Events: The 14th Paediatric Epilepsy Research Retreat and a Joint Research Event with the Epilepsy Research Institute UK were significant highlights, fostering collaboration and knowledge exchange.

Research Goals

The research programme focuses on three main workstreams:

  1. Understanding Childhood Epilepsies: Aims to uncover the medical causes of epilepsy and how it affects development and behaviour.
  2. Outstanding Treatment: Focuses on advancing diagnostic and treatment methods to improve long-term outcomes.
  3. Outstanding Support: Addresses the broader challenges of living with epilepsy, including educational interventions and support systems for families.

Impact 

The impact of the research is evident in the improved understanding of epilepsy, better diagnostic tools, and enhanced treatment options. The programme's efforts have led to significant advancements in the field, benefiting children and young people with epilepsy.

Future Directions 

The report emphasizes the importance of continued collaboration and funding to sustain and expand the research programme. The goal is to drive early diagnosis and intervention, ultimately improving the lives of children with epilepsy.