Young boy smiles at camera wearing an orange OPM-MEG helmet

OPM-MEG

We coordinate epilepsy research that improves diagnosis and treatments for children and young people, putting them at the heart of everything we do.

The cutting edge of epilepsy diagnosis

OPM-MEG technology transforms epilepsy diagnosis into a much gentler, less intrusive experience, allowing for more accurate data collection, earlier diagnosis and interventions, and better management, treatment and health outcomes.

Optically pumped magnetoencephalography (OPM-MEG) is the result of a collaboration between Young Epilepsy’s Research team and the University of Nottingham, University College London's Institute of Neurology, the UCL Wellcome Centre for Human Neuroimaging, Cerca Magnetics and Magnetic Shields Ltd.

What is magnetoencephalography?

Magnetoencephalography (MEG) is a neuroimaging tool that records naturally occurring  brain function by measuring minute changes in magnetic fields produced as brain cells communicate. MEG and EEG are often the first step in epilepsy diagnosis. MEG is a vital part of neurological diagnostics and surgical evaluation. The technology has been available for many years, but with limitations.

What is OPM-MEG?

Optically pumped magnetoencephalography (OPM-MEG) is the world’s first wearable, movable, brain-imaging system. OPM-MEG uses sensors embedded in a helmet designed specifically for children. It is 10 times more sensitive than current MEG technology. OPM-MEG offers earlier and more accurate diagnosis through better-quality data, allowing for earlier intervention, and better treatment options and outcomes for children.

Why is early diagnosis important?

Around half of people diagnosed never learn what causes their epilepsy. But the sooner we know the cause of someone’s epilepsy, the sooner we know how it is affecting them, and how best to manage and treat it. Early diagnosis is also better for the person’s understanding of their condition.

Why is early intervention important? 

The longer a child has undiagnosed and untreated epilepsy, the longer they are at risk of neurological damage. Also, people with epilepsy often have other developmental needs. Early intervention from a range of health care professionals can, therefore, be critical to improving health outcomes and quality of life for children with epilepsy. 

The brains behind OPM-MEG

Meet the research team behind OPM-MEG

Christine smiling at the camera

Postdoctoral Research Fellow

Dr Christine Embury

Christine smiling at the camera

Postdoctoral Research Fellow

Dr Christine Embury

Dr Christine Embury is a postdoctoral research fellow running the OPM-MEG project at Young Epilepsy. 

 

She completed her PhD in Neuroscience in 2021 from the University of Nebraska Omaha, discussing the effects of diabetes on cognition and the brain using MEG. She has published over 40 peer-reviewed publications. 

 

Christine has extensive experience in MEG and the applications of the technique in clinical populations. She used techniques explored during her doctorate for understanding the brain and the changes induced by development and aging, as well as during disease processes like HIV-associated neurocognitive disorder, cerebral palsy, and Alzheimer’s. 

 

Her current research focuses on localising epileptic foci in the brains of children with epilepsy using the ground-breaking new iteration of MEG called OPM-MEG, which allows for more accessible and precise imaging, in hopes to enable better surgical outcomes in the future. 

 

Christine’s inspiration for the work stems from a desire to see real change for people’s lives with real-life applications of clinical translational research. Her hobbies include traveling and exploring new places and baking for her friends and family.

Zelekha smiling at the camera

Postdoctoral Researcher and Trainee Clinical Physiologist

Dr Zelekha A Seedat

Zelekha smiling at the camera

Postdoctoral Researcher and Trainee Clinical Physiologist

Dr Zelekha A Seedat

Dr. Zelekha A Seedat joined Young Epilepsy as a post-doctoral researcher in 2021, contributing to the establishment of the OPM-MEG research facility and conducting tests on healthy adults and children. She is currently training as a clinical physiologist in EEG while continuing to support ongoing OPM-MEG research.  

  

Zelekha’s background is in academia, having acquired a Master’s degree in physics with medical physics from the University of Nottingham in 2017. Following this, she completed a PhD in MEG analysis methods at the same institution under the supervision of Professors Matthew Brookes and Karen Mullinger in 2022. She has also recently completed a Postgraduate Certificate in Neurophysiology and is working toward obtaining professional qualifications in clinical EEG. Through her academic work she published several first author papers and collaborated on many more. Zelekha has also presented at both national and international conferences, winning a Young Investigator award at ISACM in Japan in 2023.  

  

During her doctoral studies, Zelekha had the opportunity to focus on paediatric epilepsy using MEG, a field that perfectly aligned with Young Epilepsy's objectives for their OPM-MEG suite. She is deeply intrigued by the ability of MEG and EEG to detect tiny brain waves, which provide insights into both healthy and pathological brain activity. They’re highly interested in moving OPM-MEG into the clinical sphere through comparison with EEG.  

  

In their free time Zelekha enjoys spending time with her cat and exploring museums & gardens with her husband. She is also passionate about gardening, cooking, and crochet.

Kelly St Pier smiling at the camera

Diagnostic Service Manager

Kelly St. Pier

Kelly St Pier smiling at the camera

Diagnostic Service Manager

Kelly St. Pier

Kelly St. Pier was appointed to Young Epilepsy in 2019 as a Clinical Scientist specializing in Neurophysiology. In September 2021, she transitioned into a senior management role overseeing the diagnostic EEG service and the OPM-MEG research facility at Young Epilepsy.  

  

Kelly is a HCPC registered Clinical Scientist and has achieved a 1st Class BSc (Hons) in Physiological Measurement (Clinical Neurophysiology) and two masters level certifications (Scientific Training Pathway (STP) Equivalency with the Academy of Healthcare Science and Chartered Scientist Status (CSci) with the Science Council) alongside her UK professional body qualifications.  

  

Kelly's specialization and passion for paediatric EEG and complex epilepsy began in 2000 at Great Ormond Street Children's Hospital (GOSH). She later managed the video-telemetry and invasive EEG service at GOSH from 2008 to 2018. Through her role at GOSH, she maintained a strong connection with Young Epilepsy over the years.  

  

Kelly played a significant role in leading the Chartered Scientist registration license for ANS and previously served as Executive Director and Registrar of the Registration Council for Clinical Physiologists (RCCP). She is also a Chartered Scientist (CSci) and a Fellow of the Association of Neurophysiological Scientists (ANS). She has held several key national leadership roles, including serving on the ANS professional council since 2005. Her roles within the council have included ANS Honorary Chair, Vice Chair, Secretary, and Membership Secretary.  

  

Her decision to join Young Epilepsy was primarily driven by the opportunity to be involved in ground-breaking research. Her enjoyment is also sustained by the continued collaboration with Professor Helen Cross, who leads the research program across UCL GOS ICH, Great Ormond Street Hospital, and Young Epilepsy. Additionally, Kelly is passionate about quality improvement, patient safety, and professional regulation. This follows through to her current role at Young Epilepsy, where she also serves as an expert and technical assessor for the United Kingdom Accreditation Service (UKAS), specifically for their Improving Quality in Physiological Services (IQIPS) accreditation scheme. This scheme aims to enhance services, care, and safety for patients undergoing physiological tests, examinations, and procedures across the UK.  

  

Outside of her professional life, Kelly is married with three sons and enjoys aerial yoga and paddleboarding in her spare time. 

Caroline smiling at the camera

Clinical Scientist

Caroline Scott

Caroline smiling at the camera

Clinical Scientist

Caroline Scott

Caroline Scott joined the Young Epilepsy team in 2024 as a clinical scientist focused solely in paediatric EEG where she has cultivated a deep expertise since 2003. Alongside performing EEGs on a multitude of patients, she helps train staff in epilepsy & EEG understanding, supports the outpatient service, and works to develop the Magnetoencephalography (MEG) facility within the organisation.  

  

Caroline holds a BSc in Clinical Physiology and an MSc in Epileptology from King’s College London. She is also a Chartered Scientist (CSci) and a member of the Association of Neurophysiological Scientists (ANS).  

  

Caroline worked for nearly 25 years in the NHS; she began her training in Clinical Neurophysiology in Ipswich and later moved to Guy’s and St Thomas’ Foundation Trust, where she worked at the Evelina Children’s Hospital. There, she honed her skills in paediatric and neonatal EEG. After spending 10 years at Evelina, she transitioned to Birmingham Children’s Hospital to lead the Video Telemetry Service, focusing on long-term monitoring and epilepsy surgery. During her 10 years in Birmingham, she specialized in seizure semiology, long-term EEG monitoring, and invasive EEG recordings.  

  

Passionate about education, Caroline has been committed to teaching others within her profession and those interested in epilepsy. She regularly delivers talks, lectures, and presentations.  

  

When not operating EEGs, Caroline enjoys reading, gardening, knitting, and lifting weights at the gym.  

With OPM-MEG it’s going to be more of a family-friendly environment, where you can bring your child’s favourite toys and their siblings along.
Sam's Mum Tracey

The centre’s peaceful surroundings, with therapeutic sensory garden, and the diagnostic suite’s pleasing design provide a calm, reassuring environment that puts children, young people and their families immediately at ease.

We are delighted to have had the help of a Chelsea Flower Show Gold Medalist in the creation of the Centre’s wonderful outdoor space. Having been diagnosed with epilepsy himself, he design a sensory garden with the child and their family at the heart.

Support our work

You can help children and young people like Sam have more accurate diagnosis and better treatment by supporting Young Epilepsy's research partnership.

Please donate today to help fund research that transforms the lives of children and young people with epilepsy. Together we create possible.

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Magnetoencephalography (MEG) is a neuroimaging tool that records naturally occurring brain function by measuring minute changes in magnetic fields produced as brain cells communicate. It is a vital part of neurological diagnostics and surgical evaluation. MEG has existed as a brain scanning technology for many years, but the old design has critical limitations.

We have developed a new wearable, MEG system, known as OPM-MEG.

The new technology uses a different type of sensor, optically pumped magnetometers (OPM), which don’t need cryogenic cooling to work. In the new system the child wears a helmet with sensors attached, meaning that the sensors are closer to the scalp, and crucially, the new system allows children to move within an area of zero magnetic field created by the new lightweight shielded Mu-room, where the scan is carried out.

OPM-MEG is 10 times more sensitive than traditional MEG systems. This is largely due to the sensors’ placement in a wearable helmet rather than a in a fixed adult-sized hood. 

Whilst these imaging tools both measure brain function, they measure different things. EEG measures electrical activity in the brain whereas OPM-MEG measures magnetic fields in the brain and is therefore more accurate. EEG is currently widely used but OPM MEG is brand new and not yet available for clinical use. Both will have an important role to play in the diagnosis of epilepsy in the future.